Can I use RDIMM on my personal computer?

RDIMMs are primarily designed for server and enterprise-grade systems, so they are not compatible with standard desktop or consumer motherboards (UDIMMs). You'll need to check your motherboard specifications to see if it supports RDIMMs.
 

What are the main differences between UDIMMs, RDIMMs

UDIMM
Unbuffered memory modules are the most common type of RAM used in modern PCs. These are just a type of DIMM and for most users the names are interchangeable. As the name suggests, UDIMMs do not have a buffer or a register between the memory controller and the memory chips. The memory controller, which you’ll find in the processor package itself, communicates directly with the memory chips.

RDIMM
Registered DIMMs are primarily used in workstations and servers where higher reliability and stability are paramount. RDIMMs include a register, or buffer, between the memory controller and the memory chips to help stabilize and manage the electrical load of the memory modules. This allows RDIMMs to support larger memory capacities than is possible with UDIMMs. RDIMMs tend to support ECC (Error-Correcting Code), which helps to detect and correct data corruption as well, for improved reliability.

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